Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay

Discovery of Targetable Genetic Alterations in NSCLC Patients with Different Metastatic Patterns Using a MassARRAY-Based Circulating Tumor DNA Assay

Circulating tumor DNA (ctDNA) has shown great promise as a minimally invasive liquid biopsy for personalized cancer diagnostics especially among metastatic patients. Here, we used a novel sensitive assay to detect clinically relevant mutations in ctDNA in blood plasma from metastatic non-small cell...

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Bibliographic Details
Main Authors: Yassine Belloum, Melanie Janning, Malte Mohme, Ronald Simon, Jolanthe Kropidlowski, Alexander Sartori, Darryl Irwin, Manfred Westphal, Katrin Lamszus, Sonja Loges, Sabine Riethdorf, Klaus Pantel, Harriet Wikman
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
lung cancer
ctDNA
mutations
liquid biopsy
brain metastases
Online Access:https://www.mdpi.com/2073-4409/9/11/2337

Internet

https://www.mdpi.com/2073-4409/9/11/2337

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