A qPCR technology for direct quantification of methylation in untreated DNA

Abstract DNA methylation is important for gene expression and alterations in DNA methylation are involved in the development and progression of cancer and other major diseases. Analysis of DNA methylation patterns has until now been dependent on either a chemical or an enzymatic pre-treatment, which...

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Bibliographic Details
Main Authors: Kamilla Kolding Bendixen, Maria Mindegaard, Samantha Epistolio, Giulia Dazio, Francesco Marchi, Paolo Spina, Eva C. Arnspang, Mette Soerensen, Ulf Bech Christensen, Milo Frattini, Rasmus Koefoed Petersen
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40873-y