Anticancer potential of 3-hydroxypyridine-2-carboxaldehyde N(4)-methyl and pyrrolidinylthiosemicarbazones and their Zn(II) complexes in different cancers via targeting MAPK superfamily signaling pathway

Anticancer potential of 3-hydroxypyridine-2-carboxaldehyde N(4)-methyl and pyrrolidinylthiosemicarbazones and their Zn(II) complexes in different cancers via targeting MAPK superfamily signaling pathway

Zinc(II) complexes of 3-hydroxy-2-formylpyridine N(4)-methylthiosemicarbazone (1) and 3-hydroxy-2-formylpyridine N(4)-pyrrolidinyl thiosemicarbazone (2) respectively have been synthesized and characterized by elemental analysis, IR, UV–Vis, 1H NMR spectroscopy and mass spectrometry. These compounds...

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Bibliographic Details
Main Authors: Nerina Shahi, Vivek Pandey, Ankita Pathak, Ram Sundar Thapa, Prabina Pokhrel, Yuba Raj Pokharel, Paras Nath Yadav
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Results in Chemistry
Subjects:
Anti-cancer activities
ESI-mass spectrometry
3-Hydroxypyridine
Thiosemicarbazone
ZN(II) complexes
MAPK signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715621000096

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http://www.sciencedirect.com/science/article/pii/S2211715621000096

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