Structural analysis of the housecleaning nucleoside triphosphate pyrophosphohydrolase MazG from Mycobacterium tuberculosis

Structural analysis of the housecleaning nucleoside triphosphate pyrophosphohydrolase MazG from Mycobacterium tuberculosis

The housecleaning enzyme of Mycobacterium tuberculosis (Mtb), MazG, is a nucleoside triphosphate pyrophosphohydrolase (NTP-PPase) and can hydrolyze all canonical or non-canonical NTPs into NMPs and pyrophosphate. The Mycobacterium tuberculosis MazG (Mtb-MazG) contributes to antibiotic resistance in...

Full description

Bibliographic Details
Main Authors: Sen Wang, Baocai Gao, Anke Chen, Zhifei Zhang, Sheng Wang, Liangdong Lv, Guoping Zhao, Jixi Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Microbiology
Subjects:
Mycobacterium tuberculosis
MazG
NTP pyrophosphatases
crystal structure
SAXS
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1137279/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1137279/full

Similar Items