Development of Sustained Release Baricitinib Loaded Lipid-Polymer Hybrid Nanoparticles with Improved Oral Bioavailability

Development of Sustained Release Baricitinib Loaded Lipid-Polymer Hybrid Nanoparticles with Improved Oral Bioavailability

Baricitinib (BTB) is an orally administered Janus kinase inhibitor, therapeutically used for the treatment of rheumatoid arthritis. Recently it has also been approved for the treatment of COVID-19 infection. In this study, four different BTB-loaded lipids (stearin)-polymer (Poly(<span style="...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Md. Khalid Anwer, Essam A. Ali, Muzaffar Iqbal, Mohammed Muqtader Ahmed, Mohammed F. Aldawsari, Ahmed Al Saqr, Mohd Nazam Ansari, M. Ali Aboudzadeh
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: MDPI AG 2021-12-01
Cyfres:Molecules
Pynciau:
baricitinib
bioavailability
encapsulation
hybrid nanoparticles
poly(<span style="font-variant: small-caps">d</span>,<span style="font-variant: small-caps">l</span>-lactide-coglycolide)
stearin
Mynediad Ar-lein:https://www.mdpi.com/1420-3049/27/1/168

Rhyngrwyd

https://www.mdpi.com/1420-3049/27/1/168

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