Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study

Abstract Background Major depressive disorder (MDD) has a significant impact on global burden of disease. Complications in clinical management can occur when response to pharmacological modalities is considered inadequate and symptoms persist (treatment-resistant depression (TRD)). We aim to investi...

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Bibliographic Details
Main Authors: Vasilios Karageorgiou, Francesco Casanova, Jessica O’Loughlin, Harry Green, Trevelyan J. McKinley, Jack Bowden, Jessica Tyrrell
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12916-023-03001-7