Kernel density weighted loess normalization improves the performance of detection within asymmetrical data

<p>Abstract</p> <p>Background</p> <p>Normalization of gene expression data has been studied for many years and various strategies have been formulated to deal with various types of data. Most normalization algorithms rely on the assumption that the number of up-regulate...

Full description

Bibliographic Details
Main Authors: Chu Tzu-Ming, Hsieh Wen-Ping, Lin Yu-Min, Wolfinger Russell D
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/222