Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain

Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain

Abstract Aggregation of α-synuclein (α-syn) is the cornerstone of neurodegenerative diseases termed synucleinopathies, which include Parkinson’s Disease (PD), Dementia with Lewy Bodies (DLB), and Multiple System Atrophy (MSA). These synucleinopathies are characterized by the deposit of aggregated α-...

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Bibliographic Details
Main Authors: Margaux Teil, Sandra Dovero, Mathieu Bourdenx, Marie-Laure Arotcarena, Morgane Darricau, Gregory Porras, Marie-Laure Thiolat, Inés Trigo-Damas, Celine Perier, Cristina Estrada, Nuria Garcia-Carrillo, María Trinidad Herrero, Miquel Vila, José A. Obeso, Erwan Bezard, Benjamin Dehay
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00579-w

Internet

https://doi.org/10.1038/s41531-023-00579-w

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