A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport

Sterol traffic between the endoplasmic reticulum (ER) and plasma membrane (PM) is a fundamental cellular process that occurs by a poorly understood non-vesicular mechanism. We identified a novel, evolutionarily diverse family of ER membrane proteins with StART-like lipid transfer domains and studied...

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Bibliographic Details
Main Authors: Alberto T Gatta, Louise H Wong, Yves Y Sere, Diana M Calderón-Noreña, Shamshad Cockcroft, Anant K Menon, Tim P Levine
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-05-01
Series:eLife
Subjects:
membrane contact site
lipid traffic
cholesterol
ergosterol
StART protein
polyene
Online Access:https://elifesciences.org/articles/07253

Internet

https://elifesciences.org/articles/07253

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