CXCR5+CD8 T cells: Potential immunotherapy targets or drivers of immune-mediated adverse events?

CXCR5+CD8 T cells have attracted significant interest within multiple areas of immunology, cancer, and infection. This is in part due to their apparent dual functionality. These cells perform as cytotoxic cells in a variety of infection states including LCMV, HBV, HIV and SIV. However, CXCR5+CD8 T c...

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Bibliographic Details
Main Authors: Christi N. Turner, Genevieve N. Mullins, Katrina K. Hoyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1034764/full