Cholangiocarcinoma-on-a-chip: A human 3D platform for personalised medicine

Cholangiocarcinoma-on-a-chip: A human 3D platform for personalised medicine

Background & Aims: Cholangiocarcinoma (CCA) is a primary liver tumour characterised by a poor prognosis and limited therapeutic options. Available 3D human CCA models fail to faithfully recapitulate the tumour niche. We aimed to develop an innovative patient-specific CCA-on-chip platform. Me...

Full description

Bibliographic Details
Main Authors: Michela Anna Polidoro, Erika Ferrari, Cristiana Soldani, Barbara Franceschini, Giuseppe Saladino, Arianna Rosina, Andrea Mainardi, Francesca D’Autilia, Nicola Pugliese, Guido Costa, Matteo Donadon, Guido Torzilli, Simona Marzorati, Marco Rasponi, Ana Lleo
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:JHEP Reports
Subjects:
Liver-on-chip
Cholangiocarcinoma
Microfluidics
Tumour microenvironment
Cell–cell crosstalk
Drug testing
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923002410

Internet

http://www.sciencedirect.com/science/article/pii/S2589555923002410

Similar Items