Formononetin alleviates diabetic cardiomyopathy by inhibiting oxidative stress and upregulating SIRT1 in rats

Objective: To evaluate the effect of formononetin on type 2 diabetic cardiomyopathy. Methods: Diabetes was induced by feeding high-fat diet for 2 weeks and administration of 35 mg/kg of streptozotocin in rats. Formononetin was administered at 10, 20 and 40 mg/kg for 16 weeks once a day. Plasma gluco...

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Bibliographic Details
Main Authors: Manisha J Oza, Yogesh A Kulkarni
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2020;volume=10;issue=6;spage=254;epage=262;aulast=Oza