Distinct migration and contact dynamics of resting and IL-2-activated human natural killer cells

Natural killer (NK) cells serve as one of the first lines of defense against viral infections and transformed cells. NK cell cytotoxicity is not dependent on antigen presentation by target cells, but is dependent on integration of activating and inhibitory signals triggered by receptor–ligand intera...

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Bibliographic Details
Main Authors: Per Erik Olofsson, Elin eForslund, Bruno eVanherberghen, Ksenia eChechet, Oscar eMickelin, Alexander eRivera Ahlin, Tobias eEverhorn, Björn eÖnfelt
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00080/full