Antihyperglycemic Potential of <i>Spondias mangifera</i> Fruits via Inhibition of 11β-HSD Type 1 Enzyme: In Silico and In Vivo Approach

Antihyperglycemic Potential of <i>Spondias mangifera</i> Fruits via Inhibition of 11β-HSD Type 1 Enzyme: In Silico and In Vivo Approach

The 11 β- hydroxysteroid dehydrogenase 1 (11 β-HSD1) is hypothesized to play a role in the pathogenesis of type 2 diabetes and its related complications. Because high glucocorticoid levels are a risk factor for metabolic disorders, 11β-HSD1 might be a viable therapeutic target. In this investigation...

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Bibliographic Details
Main Authors: Shadma Wahab, Mohammad Khalid, Mohammed H. Alqarni, Mohamed Fadul A. Elagib, Ghadah Khaled Bahamdan, Ahmed I. Foudah, Tariq M. Aljarba, Mons S. Mohamed, Nazik Salih Mohamed, Muhammad Arif
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Journal of Clinical Medicine
Subjects:
natural products
hypoglycemia
<i>Spondias mangifera</i>
anti-hyperglycemic
11β-HSD1
in silico
Online Access:https://www.mdpi.com/2077-0383/12/6/2152

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https://www.mdpi.com/2077-0383/12/6/2152

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