A novel Anti-ROS osteoblast-specific delivery system for ankylosing spondylitis treatment via suppression of both inflammation and pathological new bone formation

A novel Anti-ROS osteoblast-specific delivery system for ankylosing spondylitis treatment via suppression of both inflammation and pathological new bone formation

Abstract Ankylosing spondylitis (AS) is a common rheumatic disorder distinguished by chronic inflammation and heterotopic ossification at local entheses sites. Currently available medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs) an...

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Bibliographic Details
Main Authors: Guan Zheng, Xiaoshuai Peng, Yunhui Zhang, Peng Wang, Zhongyu Xie, Jinteng Li, Wenjie Liu, Guiwen Ye, Yucong Lin, Guojian Li, Huatao Liu, Chenying Zeng, Lihua Li, Yanfeng Wu, Huiyong Shen
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Nanobiotechnology
Subjects:
MnFe2O4 nanoparticles
Ankylosing spondylitis
ROS scavenging
Targeted therapy
Nanomedicine
Online Access:https://doi.org/10.1186/s12951-023-01906-2

Internet

https://doi.org/10.1186/s12951-023-01906-2

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