The cortisol awakening response at admission to hospital predicts depression severity after discharge in major depressive disorder patients—A replication study

The cortisol awakening response (CAR) is a non-invasive biomarker for hypothalamic-pituitary-adrenal axis (HPA) dysregulation, reflecting accumulated stress over time. In a previous study we reported that a blunted CAR before an inpatient treatment predicted self-reported depressive symptoms six wee...

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Bibliographic Details
Main Authors: Sabrina Neyer, Michael Witthöft, Mark Cropley, Markus Pawelzik, Stefan Sütterlin, Ricardo G. Lugo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.952903/full