Increased AR expression in castration-resistant prostate cancer rapidly induces AR signaling reprogramming with the collaboration of EZH2

Increased AR expression in castration-resistant prostate cancer rapidly induces AR signaling reprogramming with the collaboration of EZH2

Elevated androgen receptor (AR) expression is a hallmark of castration-resistant prostate cancer (CRPC) and contributes to the restoration of AR signaling under the conditions of androgen deprivation. However, whether overexpressed AR alone with the stimulation of castrate levels of androgens can be...

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Chi tiết về thư mục
Những tác giả chính: Maryam Labaf, Muqing Li, Lily Ting, Breelyn Karno, Songqi Zhang, Shuai Gao, Susan Patalano, Jill A. Macoska, Kourosh Zarringhalam, Dong Han, Changmeng Cai
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Frontiers Media S.A. 2022-11-01
Loạt:Frontiers in Oncology
Những chủ đề:
androgen
androgen receptor
AR
prostate cancer
androgen-deprivation therapy
CRPC
Truy cập trực tuyến:https://www.frontiersin.org/articles/10.3389/fonc.2022.1021845/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1021845/full

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