Synthesis of new N-alkylated 6-bromoindoline-2.3-dione derivatives: Crystal structures, spectroscopic characterizations, Hirschfeld surface analyses, molecular docking studies, DFT calculations, and antibacterial activity

Synthesis of new N-alkylated 6-bromoindoline-2.3-dione derivatives: Crystal structures, spectroscopic characterizations, Hirschfeld surface analyses, molecular docking studies, DFT calculations, and antibacterial activity

Ten new isatin derivatives (2–11) were synthesized by alkylation reactions under phase transfer catalysis (PTC) conditions. Structural characterization of all compounds was performed using 1H and 13C NMR spectroscopy. The molecular and crystal structures of three compounds (4, 7, and 8) were confirm...

Full description

Bibliographic Details
Main Authors: Nohaila Rharmili, Yusuf Sert, Youssef Kandri Rodi, Fouad Ouazzani Chahdi, Amal Haoudi, Joel T. Mague, Ahmed Mazzah, Naoufal El Hachlafi, Nesrine Benkhaira, Kawtar Fikri-Benbrahim, El Mokhtar Essassi, Nada Kheira Sebbar
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Results in Chemistry
Subjects:
6-bromoisatin
Alkylation
X-ray diffraction
DFT
Hirshfeld surface
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624000341

Internet

http://www.sciencedirect.com/science/article/pii/S2211715624000341

Similar Items