Stable maternal proteins underlie distinct transcriptome, translatome, and proteome reprogramming during mouse oocyte-to-embryo transition

Stable maternal proteins underlie distinct transcriptome, translatome, and proteome reprogramming during mouse oocyte-to-embryo transition

Abstract Background The oocyte-to-embryo transition (OET) converts terminally differentiated gametes into a totipotent embryo and is critically controlled by maternal mRNAs and proteins, while the genome is silent until zygotic genome activation. How the transcriptome, translatome, and proteome are...

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Bibliographic Details
Main Authors: Hongmei Zhang, Shuyan Ji, Ke Zhang, Yuling Chen, Jia Ming, Feng Kong, Lijuan Wang, Shun Wang, Zhuoning Zou, Zhuqing Xiong, Kai Xu, Zili Lin, Bo Huang, Ling Liu, Qiang Fan, Suoqin Jin, Haiteng Deng, Wei Xie
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Genome Biology
Subjects:
Proteome
Translatome
Transcriptome
Oocyte-to-embryo transition
OET
Early embryo development
Online Access:https://doi.org/10.1186/s13059-023-02997-8

Internet

https://doi.org/10.1186/s13059-023-02997-8

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