YAP1 is essential for malignant mesothelioma tumor maintenance

YAP1 is essential for malignant mesothelioma tumor maintenance

Abstract Malignant pleural mesothelioma, a tumor arising from the membrane covering the lungs and the inner side of the ribs, is a cancer in which genetic alterations of genes encoding proteins that act on or are part of the Hippo-YAP1 signaling pathway are frequent. Dysfunctional Hippo signaling ma...

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Bibliographic Details
Main Authors: Loreley Calvet, Odette Dos-Santos, Emmanuel Spanakis, Véronique Jean-Baptiste, Jean-Christophe Le Bail, Armelle Buzy, Pascal Paul, Christophe Henry, Sandrine Valence, Colette Dib, Jack Pollard, Sukhvinder Sidhu, Jürgen Moll, Laurent Debussche, Iris Valtingojer
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Cancer
Subjects:
Malignant mesothelioma
YAP1
YAP-TEAD transcription signature
Tumor maintenance
Online Access:https://doi.org/10.1186/s12885-022-09686-y

Internet

https://doi.org/10.1186/s12885-022-09686-y

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