Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection
Summary: T helper (Th)17 cells mediate both protective anti-bacterial immune responses and autoimmune pathogenesis, but the distinct pathways regulating these Th17 responses remain unclear. Retinoid-related orphan receptor γ t (RORγt) is a master transcription factor that governs Th17 cell generatio...
Asıl Yazarlar: | , , , , , , |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Elsevier
2024-11-01
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Seri Bilgileri: | Cell Reports |
Konular: | |
Online Erişim: | http://www.sciencedirect.com/science/article/pii/S2211124724013020 |