Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection

Summary: T helper (Th)17 cells mediate both protective anti-bacterial immune responses and autoimmune pathogenesis, but the distinct pathways regulating these Th17 responses remain unclear. Retinoid-related orphan receptor γ t (RORγt) is a master transcription factor that governs Th17 cell generatio...

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Detaylı Bibliyografya
Asıl Yazarlar: Xiancai Zhong, Hongmin Wu, Wencan Zhang, Yun Shi, Yousang Gwack, Hai-hui Xue, Zuoming Sun
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Elsevier 2024-11-01
Seri Bilgileri:Cell Reports
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2211124724013020