Single cell transcriptomics reveals dysregulated cellular and molecular networks in a fragile X syndrome model.
Despite advances in understanding the pathophysiology of Fragile X syndrome (FXS), its molecular basis is still poorly understood. Whole brain tissue expression profiles have proved surprisingly uninformative, therefore we applied single cell RNA sequencing to profile an FMRP deficient mouse model w...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-06-01
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Series: | PLoS Genetics |
Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010221&type=printable |