A Ribosome Interaction Surface Sensitive to mRNA GCN Periodicity

A Ribosome Interaction Surface Sensitive to mRNA GCN Periodicity

A longstanding challenge is to understand how ribosomes parse mRNA open reading frames (ORFs). Significantly, GCN codons are over-represented in the initial codons of ORFs of prokaryote and eukaryote mRNAs. We describe a ribosome rRNA-protein surface that interacts with an mRNA GCN codon when next i...

Full description

Bibliographic Details
Main Authors: Kristen Scopino, Elliot Williams, Abdelrahman Elsayed, William A. Barr, Daniel Krizanc, Kelly M. Thayer, Michael P. Weir
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Biomolecules
Subjects:
ribosome translocation
molecular dynamics
mRNA GCN periodicity
A-site decoding center
codon adjacency
Online Access:https://www.mdpi.com/2218-273X/10/6/849

Internet

https://www.mdpi.com/2218-273X/10/6/849

Similar Items