Ligand determinants of fatty acid activation of the pronociceptive ion channel TRPA1

Background and purpose. Arachidonic acid (AA) and its derivatives are important modulators of cellular signalling. The transient receptor potential cation channel subfamily A, member 1 (TRPA1) is a cation channel with important functions in mediating cellular responses to noxious stimuli and inflamm...

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Bibliographic Details
Main Authors: William John Redmond, Liuqiong Gu, Maxime Camo, Peter McIntyre, Mark Connor
Format: Article
Language:English
Published: PeerJ Inc. 2014-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/248.pdf