Potent anti-inflammatory activity of the lectin-like domain of TNF in joints

Potent anti-inflammatory activity of the lectin-like domain of TNF in joints

In view of the crucial role of tumor necrosis factor (TNF) in joint destruction, TNF inhibitors, including neutralizing anti-TNF antibodies and soluble TNF receptor constructs, are commonly used therapeutics for the treatment of arthropathies like rheumatoid arthritis (RA). However, not all patients...

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Bibliographic Details
Main Authors: Ana Carolina Matias Dinelly Pinto, Rodolfo de Melo Nunes, Igor Albuquerque Nogueira, Bernhard Fischer, Rudolf Lucas, Virgínia Claudia Carneiro Girão-Carmona, Vivian Louise Soares de Oliveira, Flavio Almeida Amaral, Georg Schett, Francisco Airton Castro Rocha
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
arthritis
neutrophils
cytokines
inflammation
tumor necrosis factor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1049368/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1049368/full

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