An Adenovirus-Based Recombinant Herpes Simplex Virus 2 (HSV-2) Therapeutic Vaccine Is Highly Protective against Acute and Recurrent HSV-2 Disease in a Guinea Pig Model

An Adenovirus-Based Recombinant Herpes Simplex Virus 2 (HSV-2) Therapeutic Vaccine Is Highly Protective against Acute and Recurrent HSV-2 Disease in a Guinea Pig Model

Genital herpes (GH) has become one of the most common sexually transmitted diseases worldwide, and it is spreading rapidly in developing countries. Approximately 90% of GH cases are caused by HSV-2. Therapeutic HSV-2 vaccines are intended for people already infected with HSV-2 with the goal of reduc...

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Bibliographic Details
Main Authors: Mingming Wan, Xiao Yang, Jie Sun, Xue Ding, Zhijun Chen, Weiheng Su, Linjun Cai, Ali Hou, Bo Sun, Feng Gao, Chunlai Jiang, Yan Zhou
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Viruses
Subjects:
HSV-2
recombinant adenovirus
therapeutic vaccine
Online Access:https://www.mdpi.com/1999-4915/15/1/219

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https://www.mdpi.com/1999-4915/15/1/219

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