Case Report: A Novel Heterozygous Mutation of CD2AP in a Chinese Family With Proteinuria Leads to Focal Segmental Glomerulosclerosis

Case Report: A Novel Heterozygous Mutation of CD2AP in a Chinese Family With Proteinuria Leads to Focal Segmental Glomerulosclerosis

Idiopathic focal segmental glomerulosclerosis (FSGS) is a relatively frequent kidney disorder that manifest clinically as proteinuria and progressive loss of renal function. Genetic factors play a dominant role in the occurrence of FSGS. CD2-associated protein (CD2AP) is an adapter molecule and is e...

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Bibliographic Details
Main Authors: Yu-Xing Liu, Ai-Qian Zhang, Fang-Mei Luo, Yue Sheng, Chen-Yu Wang, Yi Dong, Liangliang Fan, Lv Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Pediatrics
Subjects:
FSGS
CD2AP
mutation
heterozygote
whole-exome sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.687455/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2021.687455/full

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