Seed-induced acceleration of amyloid-β mediated neurotoxicity in vivo

Seeding of amyloid beta from one brain region to another is thought to contribute to the progression of Alzheimer’s disease, although to date most studies have depended on inoculation of animals with exogenous amyloid. Here the authors describe a genetic seed and target system in Drosophila which ma...

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Bibliographic Details
Main Authors: Ramona F. Sowade, Thomas R. Jahn
Format: Article
Language:English
Published: Nature Portfolio 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00579-4