Therapeutic Potential of Phlorotannin-Rich <i>Ecklonia cava</i> Extract on Methylglyoxal-Induced Diabetic Nephropathy in In Vitro Model

Therapeutic Potential of Phlorotannin-Rich <i>Ecklonia cava</i> Extract on Methylglyoxal-Induced Diabetic Nephropathy in In Vitro Model

Advanced glycation end-products (AGEs) play a vital role in the pathogenesis of diabetic complications. Methylglyoxal (MGO), one of the major precursors of AGEs, is a highly reactive dicarbonyl compound that plays an important role in the pathogenesis of diabetic nephropathy. This study was designed...

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Bibliographic Details
Main Authors: Chi-Heung Cho, Chang-Jun Lee, Min-Gyeong Kim, Bomi Ryu, Jun-Geon Je, Yoonsook Kim, Sang-Hoon Lee
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Marine Drugs
Subjects:
<i>Ecklonia cava</i>
phlorotannin
diabetic nephropathy
advanced glycation end-products
methylglyoxal
mouse glomerular mesangial cell
Online Access:https://www.mdpi.com/1660-3397/20/6/355

Internet

https://www.mdpi.com/1660-3397/20/6/355

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