Comparison of in vitro, in vivo, and in silico bioavailability results of different prednisone tablet formulations to assess the feasibility of possible biowaiver

Comparison of in vitro, in vivo, and in silico bioavailability results of different prednisone tablet formulations to assess the feasibility of possible biowaiver

Abstract Introduction: The immediate-release solid oral products containing very soluble and permeable drugs are candidates for the biowaiver process. This work aims to compare in vitro, in silico, and in vivo data to establish if previously published prednisone oral tablet formulations are biowai...

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Bibliographic Details
Main Authors: Leonardo Henrique Toehwé, Thiago da Silva Honorio, Luiz Claudio Rodrigues Pereira da Silva, Thalita Martins da Silva, Luciana da Rocha Pitta, Livia Deris Prado, Lucio Mendes Cabral, Helvécio Vinícius Antunes Rocha
Format: Article
Language:English
Published: Facultad de Farmacia, Universidad de Granada 2021-11-01
Series:Ars Pharmaceutica
Subjects:
prednisone
in silico simulation
bioavailability
biowaiver
Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942021000400358&tlng=en

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http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2340-98942021000400358&tlng=en

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