Profile of the tprK gene in primary syphilis patients based on next-generation sequencing.

BACKGROUND:The highly variable tprK gene of Treponema pallidum has been acknowledged to be one of the mechanisms that causes persistent infection. Previous studies have mainly focused on the heterogeneity in tprK in propagated strains using a clone-based Sanger approach. Few studies have investigate...

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Bibliographic Details
Main Authors: Dan Liu, Man-Li Tong, Xi Luo, Li-Li Liu, Li-Rong Lin, Hui-Lin Zhang, Yong Lin, Jian-Jun Niu, Tian-Ci Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6400401?pdf=render