Critical role of tristetraprolin and AU‐rich element RNA‐binding protein 1 in the suppression of cancer cell growth by globular adiponectin

Critical role of tristetraprolin and AU‐rich element RNA‐binding protein 1 in the suppression of cancer cell growth by globular adiponectin

Adiponectin exhibits potent antitumor activities. Herein, we examined the molecular mechanisms underlying suppression of tumor growth by globular adiponectin (gAcrp). We demonstrated that gAcrp suppressed B‐cell lymphoma 2 (Bcl‐2) expression, an anti‐apoptotic gene, by inducing its mRNA destabilizat...

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Bibliographic Details
Main Authors: Nirmala Tilija Pun, Amrita Khakurel, Aastha Shrestha, Sang‐Hyun Kim, Pil‐Hoon Park
Format: Article
Language:English
Published: Wiley 2018-12-01
Series:FEBS Open Bio
Subjects:
adiponectin
AUF1
Bcl‐2
hepatic cancer
TTP
Online Access:https://doi.org/10.1002/2211-5463.12541

Internet

https://doi.org/10.1002/2211-5463.12541

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