Increased levels of NETosis biomarkers in high-grade serous ovarian cancer patients’ biofluids: Potential role in disease diagnosis and management

Increased levels of NETosis biomarkers in high-grade serous ovarian cancer patients’ biofluids: Potential role in disease diagnosis and management

IntroductionHigh-grade serous ovarian cancer (HGSOC) is the second most frequent gynecological malignancy but the most lethal, partially due to the spread of the disease through the peritoneal cavity. Recent evidence has shown that, apart from their role in immune defense through phagocytosis and de...

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Bibliographic Details
Main Authors: Sarai Tomás-Pérez, Julia Oto, Cristina Aghababyan, Raquel Herranz, Aitor Cuadros-Lozano, Eva González-Cantó, Bárbara Mc Cormack, Judith Arrés, María Castaño, Fernando Cana, Laura Martínez-Fernández, Núria Santonja, Rocío Ramírez, Alejandro Herreros-Pomares, Sarai Cañete-Mota, Antoni Llueca, Josep Marí-Alexandre, Pilar Medina, Juan Gilabert-Estellés
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
high-grade serous ovarian cancer
biomarkers
NETosis
cfDNA
calprotectin
peritoneal fluid
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1111344/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1111344/full

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