Primary Human Derived Blood Outgrowth Endothelial Cells: An Appropriate In Vitro Model to Study Shiga Toxin Mediated Damage of Endothelial Cells

Primary Human Derived Blood Outgrowth Endothelial Cells: An Appropriate In Vitro Model to Study Shiga Toxin Mediated Damage of Endothelial Cells

Hemolytic uremic syndrome (HUS) is a rare disease primarily characterized by hemolytic anemia, thrombocytopenia, and acute renal failure. Endothelial damage is the hallmark of the pathogenesis of HUS with an infection with the Shiga toxin (Stx) producing <i>Escherichia coli</i> (STEC-HUS...

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Bibliographic Details
Main Authors: Wouter J. C. Feitz, Nicole C. A. J. van de Kar, Ian Cheong, Thea J. A. M. van der Velden, Carolina G. Ortiz-Sandoval, Dorothea Orth-Höller, Lambert P. J. W. van den Heuvel, Christoph Licht
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Toxins
Subjects:
hemolytic uremic syndrome
shiga toxin
blood outgrowth endothelial cells
Online Access:https://www.mdpi.com/2072-6651/12/8/483

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https://www.mdpi.com/2072-6651/12/8/483

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