Evidence for Status Epilepticus and Pro-Inflammatory Changes after Intranasal Kainic Acid Administration in Mice.

Evidence for Status Epilepticus and Pro-Inflammatory Changes after Intranasal Kainic Acid Administration in Mice.

Kainic acid (KA) is routinely used to elicit status epilepticus (SE) and epileptogenesis. Among the available KA administration protocols, intranasal instillation (IN) remains understudied. Dosages of KA were instilled IN in mice. Racine Scale and Video-EEG were used to assess and quantify SE onset....

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Bibliographic Details
Main Authors: Mounira Sabilallah, Pierre Fontanaud, Nathalie Linck, Badreddine Boussadia, Ronan Peyroutou, Thibault Lasgouzes, François A Rassendren, Nicola Marchi, Helene E Hirbec
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4786335?pdf=render

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http://europepmc.org/articles/PMC4786335?pdf=render

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