Dual Roles of Ascidian Chondromodulin-1: Promoting Cell Proliferation Whilst Suppressing the Growth of Tumor Cells

Chondromodulin-1 (ChM-1) is an extracellular matrix protein that plays crucial roles in tumor cell growth and angiogenesis in vertebrates and humans. ChM-1 is highly expressed in the invertebrate Ciona savignyi, a marine ascidian chosen as a model. The effect of the recombinant Ciona mature ChM-1 pe...

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Bibliographic Details
Main Authors: Xiaoju Dou, Xiang Li, Haiyan Yu, Bo Dong
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/16/2/59