Response of methicillin-resistant Staphylococcus aureus to amicoumacin A.

Amicoumacin A exhibits strong antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA), hence we sought to uncover its mechanism of action. Genome-wide transcriptome analysis of S. aureus COL in response to amicoumacin A showed alteration in transcription of genes specifying...

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Bibliographic Details
Main Authors: Amrita Lama, Jan Pané-Farré, Tai Chon, Anna M Wiersma, Clarissa S Sit, John C Vederas, Michael Hecker, Michiko M Nakano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3316591?pdf=render