ALKBH5-mediated N6-methyladenosine modification of TRERNA1 promotes DLBCL proliferation via p21 downregulation

ALKBH5-mediated N6-methyladenosine modification of TRERNA1 promotes DLBCL proliferation via p21 downregulation

Abstract Long noncoding RNAs (lncRNAs) have crucial functions in the tumorigenesis and metastasis of cancers. N6-methyladenosine (m6A) modification of RNA is an important epigenetic regulatory mechanism in various malignancies. Nevertheless, the mechanism of m6A-modified lncRNA in diffuse large B ce...

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Bibliographic Details
Main Authors: Wei Song, Fei Fei, Fengchang Qiao, Zuyi Weng, Yuanxun Yang, Bei Cao, Jing Yue, Jiaxuan Xu, Meihong Zheng, Juan Li
Format: Article
Language:English
Published: Nature Publishing Group 2022-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00819-7

Internet

https://doi.org/10.1038/s41420-022-00819-7

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