Maternal Nutrient Restriction Disrupts Gene Expression and Metabolites Associated with Urea Cycle, Steroid Synthesis, Glucose Homeostasis, and Glucuronidation in Fetal Calf Liver

Maternal Nutrient Restriction Disrupts Gene Expression and Metabolites Associated with Urea Cycle, Steroid Synthesis, Glucose Homeostasis, and Glucuronidation in Fetal Calf Liver

This study aimed to understand the mechanisms underlying the effects of maternal undernutrition (MUN) on liver growth and metabolism in Japanese Black fetal calves (8.5 months in utero) using an approach that integrates metabolomics and transcriptomics. Dams were fed 60% (low-nutrition; LN) or 120%...

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Bibliographic Details
Main Authors: Susumu Muroya, Yi Zhang, Kounosuke Otomaru, Kazunaga Oshima, Ichiro Oshima, Mitsue Sano, Sanggun Roh, Koichi Ojima, Takafumi Gotoh
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Metabolites
Subjects:
fetal programming
glucuronidation
fetal growth restriction (fgr)
liver
maternal nutrient restriction
steroid synthesis
Online Access:https://www.mdpi.com/2218-1989/12/3/203

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https://www.mdpi.com/2218-1989/12/3/203

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