Interplay between CXCR4 and CCR2 regulates bone marrow exit of dendritic cell progenitors

Summary: Conventional dendritic cells (cDCs) are found in most tissues and play a key role in initiation of immunity. cDCs require constant replenishment from progenitors called pre-cDCs that develop in the bone marrow (BM) and enter the blood circulation to seed all tissues. This process can be mar...

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Bibliographic Details
Main Authors: Mariana Pereira da Costa, Carlos M. Minutti, Cécile Piot, Evangelos Giampazolias, Ana Cardoso, Mar Cabeza-Cabrerizo, Neil C. Rogers, Marta Lebrusant-Fernandez, Chrysante S. Iliakis, Andreas Wack, Caetano Reis e Sousa
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723008926