Alternative DNA secondary structure formation affects RNA polymerase II promoter-proximal pausing in human

Alternative DNA secondary structure formation affects RNA polymerase II promoter-proximal pausing in human

Abstract Background Alternative DNA secondary structures can arise from single-stranded DNA when duplex DNA is unwound during DNA processes such as transcription, resulting in the regulation or perturbation of these processes. We identify sites of high propensity to form stable DNA secondary structu...

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Bibliographic Details
Main Authors: Karol Szlachta, Ryan G. Thys, Naomi D. Atkin, Levi C. T. Pierce, Stefan Bekiranov, Yuh-Hwa Wang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Genome Biology
Subjects:
DNA secondary structure
RNA polymerase II promoter-proximal pausing
Online Access:http://link.springer.com/article/10.1186/s13059-018-1463-8

Internet

http://link.springer.com/article/10.1186/s13059-018-1463-8

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