Structure-function analysis of nucleolin and ErbB receptors interactions.

BACKGROUND: The ErbB receptor tyrosine kinases and nucleolin are major contributors to malignant transformation. Recently we have found that cell-surface ErbB receptors interact with nucleolin via their cytoplasmic tail. Overexpression of ErbB1 and nucleolin leads to receptor phosphorylation, dimeri...

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Bibliographic Details
Main Authors: Keren Farin, Ayelet Di Segni, Adam Mor, Ronit Pinkas-Kramarski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2700965?pdf=render