Mir-155 Downregulation by miRCURY LNA™ microRNA Inhibitor Can Increase alpha Chain Hemoglobins Expression in Erythroleukemic K562 Cell Line

Mir-155 Downregulation by miRCURY LNA™ microRNA Inhibitor Can Increase alpha Chain Hemoglobins Expression in Erythroleukemic K562 Cell Line

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Background: MicroRNAs (miRNA) are small non-coding RNAs that have a distinguished role in post- transcriptional gene expression. It’s estimated that 10-30% of human mRNAs are regulated by miRNAs. Many miRNAs profiles change during normal erythropoiesis in which some of them are stage specific.mir-15...

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Bibliographic Details
Main Authors: Shaban Alizadeh, Saeid Kaviani, Masoud Soleimani, Fatemeh Kouhkan, Ali Akbar Pourfathollah, Naser Amirizadeh, Saeid Abroun, Mehrdad Noruzinia
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2010-06-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Erythroid
Hemoglobin
miRNA
mir-155
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/241

Internet

https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/241

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