Primary microcephaly gene CENPE is a novel biomarker and potential therapeutic target for non-WNT/non-SHH medulloblastoma

Primary microcephaly gene CENPE is a novel biomarker and potential therapeutic target for non-WNT/non-SHH medulloblastoma

BackgroundNon-WNT/non-SHH medulloblastoma (MB) is one of the subtypes with the highest genetic heterogeneity in MB, and its current treatment strategies have unsatisfactory results and significant side effects. As a member of the centromere protein (CENP) family, centromeric protein E (CENPE) is a m...

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Bibliographic Details
Main Authors: Huangyi Fang, Yusong Zhang, Chengyin Lin, Zhenkai Sun, Wei Wen, Hansong Sheng, Jian Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
CENPE
non-WNT/non-SHH medulloblastoma
microcephaly
bioinformatics analysis
cell cycle
p53
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1227143/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1227143/full

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