Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue—Multi-omics Insights From the Munich MIDY Pig Model

Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue—Multi-omics Insights From the Munich MIDY Pig Model

Adipose tissue (AT) is no longer considered to be responsible for energy storage only but is now recognized as a major endocrine organ that is distributed across different parts of the body and is actively involved in regulatory processes controlling energy homeostasis. Moreover, AT plays a crucial...

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Bibliographic Details
Main Authors: Florian Flenkenthaler, Erik Ländström, Bachuki Shashikadze, Mattias Backman, Andreas Blutke, Julia Philippou-Massier, Simone Renner, Martin Hrabe de Angelis, Rüdiger Wanke, Helmut Blum, Georg J. Arnold, Eckhard Wolf, Thomas Fröhlich
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Medicine
Subjects:
diabetes
insulin deficiency
adipose tissue
proteome
transcriptome
pig model
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.751277/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.751277/full

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