Apoptosis inhibitor of macrophage (AIM)/CD5L is involved in the pathogenesis of COPD

Abstract Background Alveolar macrophages (AMs) and AM-produced matrix metalloprotease (MMP)-12 are known to play critical roles in the pathogenesis of chronic obstructive pulmonary disease (COPD). The apoptosis inhibitor of the macrophages (AIM)/CD5 molecule-like (CD5L) is a multifunctional protein...

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Bibliographic Details
Main Authors: Michiko Takimoto-Sato, Masaru Suzuki, Hiroki Kimura, Haiyan Ge, Munehiro Matsumoto, Hironi Makita, Satoko Arai, Toru Miyazaki, Masaharu Nishimura, Satoshi Konno
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-023-02508-0