Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer.

Matrix proteins are encoded by many enveloped viruses, including influenza viruses, herpes viruses, and coronaviruses. Underneath the viral envelope of influenza virus, matrix protein 1 (M1) forms an oligomeric layer critical for particle stability and pH-dependent RNA genome release. However, high-...

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Bibliographic Details
Main Authors: Lisa Selzer, Zhaoming Su, Grigore D Pintilie, Wah Chiu, Karla Kirkegaard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000827