Cross center single-cell RNA sequencing study of the immune microenvironment in rapid progressing multiple myeloma

Abstract Despite advancements in understanding the pathophysiology of Multiple Myeloma (MM), the cause of rapid progressing disease in a subset of patients is still unclear. MM’s progression is facilitated by complex interactions with the surrounding bone marrow (BM) cells, forming a microenvironmen...

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Bibliographic Details
Main Authors: William Pilcher, Beena E. Thomas, Swati S. Bhasin, Reyka G. Jayasinghe, Lijun Yao, Edgar Gonzalez-Kozlova, Surendra Dasari, Seunghee Kim-Schulze, Adeeb Rahman, Jonathan Patton, Mark Fiala, Giulia Cheloni, Taxiarchis Kourelis, Madhav V. Dhodapkar, Ravi Vij, Shaadi Mehr, Mark Hamilton, Hearn Jay Cho, Daniel Auclair, David E. Avigan, Shaji K. Kumar, Sacha Gnjatic, Li Ding, Manoj Bhasin
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-022-00340-x