ICOS-expressing lymphocytes promote resolution of CD8-mediated lung injury in a mouse model of lung rejection.

ICOS-expressing lymphocytes promote resolution of CD8-mediated lung injury in a mouse model of lung rejection.

Acute rejection, a common complication of lung transplantation, may promote obliterative bronchiolitis leading to graft failure in lung transplant recipients. During acute rejection episodes, CD8(+) T cells can contribute to lung epithelial injury but the mechanisms promoting and controlling CD8-med...

Full description

Bibliographic Details
Main Authors: Qiang Wu, Gail J Gardiner, Elizabeth Berry, Sarah R Wagner, Tiffany Lu, Bryan S Clay, Tamson V Moore, Caroline M Ferreira, Jesse W Williams, Andrew D Luster, Benjamin D Medoff, Judy L Cannon, Anne I Sperling, Rebecca A Shilling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3742557?pdf=render

Internet

http://europepmc.org/articles/PMC3742557?pdf=render

Similar Items