Time-resolved transcriptomic profiling of the developing rabbit’s lungs: impact of premature birth and implications for modelling bronchopulmonary dysplasia

Time-resolved transcriptomic profiling of the developing rabbit’s lungs: impact of premature birth and implications for modelling bronchopulmonary dysplasia

Abstract Background Premature birth, perinatal inflammation, and life-saving therapies such as postnatal oxygen and mechanical ventilation are strongly associated with the development of bronchopulmonary dysplasia (BPD); these risk factors, alone or combined, cause lung inflammation and alter progra...

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Bibliographic Details
Main Authors: Matteo Storti, Maria Laura Faietti, Xabier Murgia, Chiara Catozzi, Ilaria Minato, Danilo Tatoni, Simona Cantarella, Francesca Ravanetti, Luisa Ragionieri, Roberta Ciccimarra, Matteo Zoboli, Mar Vilanova, Ester Sánchez-Jiménez, Marina Gay, Marta Vilaseca, Gino Villetti, Barbara Pioselli, Fabrizio Salomone, Simone Ottonello, Barbara Montanini, Francesca Ricci
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Respiratory Research
Subjects:
Bronchopulmonary dysplasia
Premature birth
Transcriptomics
Proteomics
Lung development
Online Access:https://doi.org/10.1186/s12931-023-02380-y

Internet

https://doi.org/10.1186/s12931-023-02380-y

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